Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins

Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. Surface Plasmon Resonance assays have been performed to determine the binding affinity between PDZ domain of wild type hu...

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Enregistré dans:
Détails bibliographiques
Publié dans:Comput Struct Biotechnol J
Auteurs principaux: Lo Cascio, Ettore, Toto, Angelo, Babini, Gabriele, De Maio, Flavio, Sanguinetti, Maurizio, Mordente, Alvaro, Della Longa, Stefano, Arcovito, Alessandro
Format: Artigo
Langue:Inglês
Publié: Research Network of Computational and Structural Biotechnology 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970798/
https://ncbi.nlm.nih.gov/pubmed/33758649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.03.014
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