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Mechanical stress determines the configuration of TGFβ activation in articular cartilage
Our incomplete understanding of osteoarthritis (OA) pathogenesis has significantly hindered the development of disease-modifying therapy. The functional relationship between subchondral bone (SB) and articular cartilage (AC) is unclear. Here, we found that the changes of SB architecture altered the...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969741/ https://ncbi.nlm.nih.gov/pubmed/33731712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21948-0 |
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