OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer

c-MET is considered a driver of cancer progression, impacting tumor growth and tumor-supporting stroma. Here, we investigated the therapeutic efficacy of OMO-1, a potent and selective c-MET inhibitor, in an immunocompetent intraductal mouse model for triple-negative breast cancer (TNBC). OMO-1 reduc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:NPJ Breast Cancer
Main Authors: Steenbrugge, Jonas, Vander Elst, Niels, Demeyere, Kristel, De Wever, Olivier, Sanders, Niek N., Van Den Broeck, Wim, Ciamporcero, Eric, Perera, Timothy, Meyer, Evelyne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969607/
https://ncbi.nlm.nih.gov/pubmed/33731699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-021-00234-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados