A zebrafish forward genetic screen identifies an indispensable threonine residue in the kinase domain of PRKD2

Protein kinase D2 belongs to a family of evolutionarily conserved enzymes regulating several biological processes. In a forward genetic screen for zebrafish cardiovascular mutants, we identified a mutation in the prkd2 gene. Homozygous mutant embryos develop as wild type up to 36 h post-fertilizatio...

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Dades bibliogràfiques
Publicat a:Biol Open
Autors principals: Giardoglou, Panagiota, Bournele, Despina, Park, Misun, Kanoni, Stavroula, Dedoussis, George V., Steinberg, Susan F., Deloukas, Panos, Beis, Dimitris
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969590/
https://ncbi.nlm.nih.gov/pubmed/33597201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.058542
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