Zika Virus Envelope Domain III Recombinant Protein Delivered With Saponin-Based Nanoadjuvant From Quillaja brasiliensis Enhances Anti-Zika Immune Responses, Including Neutralizing Antibodies and Splenocyte Proliferation

Nanoadjuvants that combine immunostimulatory properties and delivery systems reportedly bestow major improvements on the efficacy of recombinant, protein-based vaccines. Among these, self-assembled micellar formulations named ISCOMs (immune stimulating complexes) show a great ability to trigger powe...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Cibulski, Samuel, Varela, Ana Paula Muterle, Teixeira, Thais Fumaco, Cancela, Martín Pablo, Sesterheim, Patrícia, Souza, Diogo Onofre, Roehe, Paulo Michel, Silveira, Fernando
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969523/
https://ncbi.nlm.nih.gov/pubmed/33746970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.632714
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