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Genomic and phenotypic heterogeneity in prostate cancer

From a clinical, morphological and molecular perspective, prostate cancer is a heterogeneous disease. Primary prostate cancers are often multifocal, having topographically and morphologically distinct tumour foci. Sequencing studies have revealed that individual tumour foci can arise as clonally dis...

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Detalhes bibliográficos
Publicado no:Nat Rev Urol
Main Authors: Haffner, Michael C., Zwart, Wilbert, Roudier, Martine P., True, Lawrence D., Nelson, William G., Epstein, Jonathan I., De Marzo, Angelo M., Nelson, Peter S., Yegnasubramanian, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969494/
https://ncbi.nlm.nih.gov/pubmed/33328650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41585-020-00400-w
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