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Facilitating Compound Entry as a Means to Discover Antibiotics for Gram-Negative Bacteria
It has been over half a century since the last class of antibiotics active against the most problematic Gram-negative bacteria was approved by the Food and Drug Administration (FDA). The major challenge with developing antibiotics to treat these infections is not drug—target engagement, but rather t...
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| Udgivet i: | Acc Chem Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969460/ https://ncbi.nlm.nih.gov/pubmed/33635073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00895 |
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