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Mouse model suggests limited role for human mesotrypsin in pancreatitis
Mesotrypsin is a low-abundance human trypsin isoform with a unique evolutionary mutation that conferred resistance to trypsin inhibitors and restricted substrate specificity. Mesotrypsin degrades the serine protease inhibitor Kazal type 1 (SPINK1) and thereby might increase risk for pancreatitis. He...
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| Publicado no: | Pancreatology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969449/ https://ncbi.nlm.nih.gov/pubmed/33526384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pan.2021.01.007 |
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