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Regulation of Superoxide by BAP31 through Its Effect on p22(phox) and Keap1/Nrf2/HO-1 Signaling Pathway in Microglia

Reactive oxygen species (ROS) production by activation of microglia is considered to be a major cause of neuronal dysfunction, which can lead to damage and death through direct oxidative damage to neuronal macromolecules or derangement of neuronal redox signaling circuits. BAP31, an integral ER memb...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Liu, Xia, Yuan, Qing, Li, Guo-xun, Jia, Cong-cong, Liu, Jing-yu, Yang, Yan-qiu, Wang, Xiao-yu, Hou, Yue, Wang, Bing
Format: Artigo
Langue:Inglês
Publié: Hindawi 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969104/
https://ncbi.nlm.nih.gov/pubmed/33777312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/1457089
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