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Structural and dynamical insights into the PH domain of p62 in human TFIIH

TFIIH is a crucial transcription and DNA repair factor consisting of the seven-subunit core. The core subunit p62 contains a pleckstrin homology domain (PH-D), which is essential for locating TFIIH at transcription initiation and DNA damage sites, and two BSD (BTF2-like transcription factors, synaps...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Okuda, Masahiko, Ekimoto, Toru, Kurita, Jun-ichi, Ikeguchi, Mitsunori, Nishimura, Yoshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969019/
https://ncbi.nlm.nih.gov/pubmed/33211877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1045
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