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Nuclear genome-wide associations with mitochondrial heteroplasmy

The role of the nuclear genome in maintaining the stability of the mitochondrial genome (mtDNA) is incompletely known. mtDNA sequence variants can exist in a state of heteroplasmy, which denotes the coexistence of organellar genomes with different sequences. Heteroplasmic variants that impair mitoch...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Nandakumar, Priyanka, Tian, Chao, O’Connell, Jared, Hinds, David, Paterson, Andrew D., Sondheimer, Neal
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968846/
https://ncbi.nlm.nih.gov/pubmed/33731350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe7520
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