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A simple fluorescent assay for the discovery of protein-protein interaction inhibitors

Due to the therapeutic potential of targeting protein-protein interactions (PPIs) there is a need for easily executed assays to perform high throughput screening (HTS) of inhibitors. We have developed and optimized an innovative and robust fluorescence-based assay for detecting PPI inhibitors, calle...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Anal Biochem
Päätekijät: Al-Mugotir, Mona, Kolar, Carol, Vance, Krysten, Kelly, David L., Natarajan, Amarnath, Borgstahl, Gloria E. O.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968734/
https://ncbi.nlm.nih.gov/pubmed/30707898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2019.01.010
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