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Counteracting Poisoning with Chemical Warfare Nerve Agents

Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of muscarinic and nicotinic membrane receptors in the ce...

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Détails bibliographiques
Publié dans:Arh Hig Rada Toksikol
Auteurs principaux: Hrvat, Nikolina Maček, Kovarik, Zrinka
Format: Artigo
Langue:Inglês
Publié: Sciendo 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968514/
https://ncbi.nlm.nih.gov/pubmed/33410774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/aiht-2020-71-3459
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