Concurrent definitive immunoradiotherapy for patients with Stage III-IV Head and Neck Cancer and Cisplatin contraindication

PURPOSE: Although cisplatin plus radiotherapy is a standard treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC), cisplatin contraindication is common. Radiation elicits and promotes tumor-directed immune-stimulation, which may potentiate anti-PD-1 therapy. We provide the f...

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Publicat a:Clin Cancer Res
Autors principals: Weiss, Jared, Sheth, Siddharth, Deal, Allision M., Grilley-Olson, Juneko, Patel, Samip, Hackman, Trevor, Blumberg, Jeffrey, Galloway, Thomas, Patel, Shetal, Zanation, Adam, Shen, Colette, Hayes, D. Neil, Hilliard, Christopher, Mehra, Ranee, McKinnon, Karen, Wang, Hsing-Hui, Weissler, Mark, Bauman, Jessica, Chera, Bhishamjit, Vincent, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968114/
https://ncbi.nlm.nih.gov/pubmed/32371539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-0230
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