Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials

STUDY QUESTION: Can asoprisnil, a selective progesterone receptor modulator, provide clinically meaningful improvements in heavy menstrual bleeding (HMB) associated with uterine fibroids with an acceptable safety profile? SUMMARY ANSWER: Uninterrupted treatment with asoprisnil for 12 months effectiv...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Reprod
Hauptverfasser: Stewart, E A, Diamond, M P, Williams, A R W, Carr, B R, Myers, E R, Feldman, R A, Elger, W, Mattia-Goldberg, C, Schwefel, B M, Chwalisz, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967793/
https://ncbi.nlm.nih.gov/pubmed/30865281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dez007
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