Rad52 SUMOylation functions as a molecular switch that determines a balance between the Rad51- and Rad59-dependent survivors

Functional telomeres in yeast lacking telomerase can be restored by rare Rad51- or Rad59-dependent recombination events that lead to type I and type II survivors, respectively. We previously proposed that polySUMOylation of proteins and the SUMO-targeted ubiquitin ligase Slx5-Slx8 are key factors in...

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Pubblicato in:iScience
Autori principali: Charifi, Ferose, Churikov, Dmitri, Eckert-Boulet, Nadine, Minguet, Christopher, Jourquin, Frédéric, Hardy, Julien, Lisby, Michael, Simon, Marie-Noëlle, Géli, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966982/
https://ncbi.nlm.nih.gov/pubmed/33748714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102231
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