Molecular pathology of thymomas: implications for diagnosis and therapy

Thymomas exhibit a unique genomic landscape, comprising the lowest on average total mutational burden among adult human cancers; a unique point mutation in the GTF2I gene in WHO type A and AB thymomas (and rarely others); almost unique KMT2A-MAML2 translocations in rare WHO type B2 and B3 thymomas;...

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Detalhes bibliográficos
Publicado no:Virchows Arch
Main Authors: Marx, Alexander, Belharazem, Djeda, Lee, De-Hyung, Popovic, Zoran V., Reißfelder, Christoph, Schalke, Berthold, Schölch, Sebastian, Ströbel, Philipp, Weis, Cleo-Aron, Yamada, Yosuke
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Review and Perspectives
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966134/
https://ncbi.nlm.nih.gov/pubmed/33674910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-021-03068-8
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