Reinforcement learning and Bayesian data assimilation for model‐informed precision dosing in oncology

Model‐informed precision dosing (MIPD) using therapeutic drug/biomarker monitoring offers the opportunity to significantly improve the efficacy and safety of drug therapies. Current strategies comprise model‐informed dosing tables or are based on maximum a posteriori estimates. These approaches, how...

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Udgivet i:CPT Pharmacometrics Syst Pharmacol
Main Authors: Maier, Corinna, Hartung, Niklas, Kloft, Charlotte, Huisinga, Wilhelm, de Wiljes, Jana
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965840/
https://ncbi.nlm.nih.gov/pubmed/33470053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12588
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