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CTLA-4 (+49A/G) Polymorphism in Type 1 Diabetes Children of Sudanese Population
Background Type 1 diabetes mellitus (T1DM) is an organ-specific T cell-mediated autoimmune disease, characterized by destruction of pancreatic islets. Cytotoxic lymphocyte antigen-4 ( CTLA-4 ) is a negative regulator of T cell proliferation, thus conferring susceptibility to autoimmunity. Aims Thi...
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| Published in: | Glob Med Genet |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Georg Thieme Verlag KG
2021
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7964255/ https://ncbi.nlm.nih.gov/pubmed/33748819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0041-1723008 |
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