Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model

Neurotrophins constitute a group of growth factor that exerts important functions in the nervous system of vertebrates. They act through two classes of transmembrane receptors: tyrosine-kinase receptors and the p75 neurotrophin receptor (p75(NTR)). The activation of p75(NTR) can favor cell survival...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Barrio, Tomás, Vidal, Enric, Betancor, Marina, Otero, Alicia, Martín-Burriel, Inmaculada, Monzón, Marta, Monleón, Eva, Pumarola, Martí, Badiola, Juan José, Bolea, Rosa
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962525/
https://ncbi.nlm.nih.gov/pubmed/33800240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052714
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