Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a tumor deriving from nasopharyngeal epithelium. Peptidyl-arginine deiminase 4 (PAD4) is a vital mediator of histone citrullination and plays an essential role in regulating disease process. Radiotherapy is an essential method to treat NPC. In this resea...

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Dettagli Bibliografici
Pubblicato in:Cell Mol Biol Lett
Autori principali: Chen, Hao, Luo, Min, Wang, Xiangping, Liang, Ting, Huang, Chaoyuan, Huang, Changjie, Wei, Lining
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962337/
https://ncbi.nlm.nih.gov/pubmed/33726680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-021-00251-2
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