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Adult pilocytic astrocytoma in the molecular era: a comprehensive review

Adult pilocytic astrocytoma (PA) is less prevalent than pediatric PA and is associated with a worse prognosis. In a literature review, we found that 88.3% of the molecular alterations in adult PA are associated with MAPK pathway dysregulation. The most common alterations are fusions of BRAF. Underst...

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Pubblicato in:CNS Oncol
Autori principali: Gregory, Timothy A, Chumbley, Lyndon B, Henson, John W, Theeler, Brett J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Medicine Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962176/
https://ncbi.nlm.nih.gov/pubmed/33448230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2020-0027
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