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Quantitative interactomics of Lck-TurboID in living human T cells unveils T cell receptor stimulation-induced proximal Lck interactors

While Lck has been widely recognized to play a pivotal role in the initiation of the T cell receptor (TCR) signaling pathway, an understanding of the precise regulation of Lck in T cells upon TCR activation remains elusive. Investigation of protein-protein interaction (PPI) using proximity labeling...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Chua, Xien Yu, Aballo, Timothy, Elnemer, William, Tran, Melanie, Salomon, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962135/
https://ncbi.nlm.nih.gov/pubmed/33185455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00616
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