The Rationale for the Intra-Articular Administration of Clodronate in Osteoarthritis

Background: Several pharmacological therapeutic approaches have been proposed to manage osteoarthritis (OA), including intra-articular (IA) injections. Although the discovery of clodronate, a bisphosphonate, dates back to the 1960s and the effects of its IA administration have been investigated for...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Moretti, Antimo, Paoletta, Marco, Liguori, Sara, Ilardi, Walter, Snichelotto, Francesco, Toro, Giuseppe, Gimigliano, Francesca, Iolascon, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Review
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962069/
https://ncbi.nlm.nih.gov/pubmed/33799992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052693
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