Local Administration of Low-Dose Nerve Growth Factor Antibody Reduced Pain in a Rat Osteoarthritis Model

Systemic injection of a nerve growth factor (NGF) antibody has been proven to have a significant relevance in relieving osteoarthritis (OA) pain, while its adverse effects remain a safety concern for patients. A local low-dose injection is thought to minimize adverse effects. In this study, OA was i...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Tian, Yuan, Onodera, Tomohiro, Terkawi, Mohamad Alaa, Iwasaki, Koji, Hishimura, Ryosuke, Liang, Dawei, Miyazaki, Takuji, Iwasaki, Norimasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962042/
https://ncbi.nlm.nih.gov/pubmed/33806315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052552
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