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Nucleophilic Aromatic Substitution of Polyfluoroarene to Access Highly Functionalized 10-Phenylphenothiazine Derivatives

Nucleophilic aromatic substitution (S(N)Ar) reactions can provide metal-free access to synthesize monosubstituted aromatic compounds. We developed efficient S(N)Ar conditions for p-selective substitution of polyfluoroarenes with phenothiazine in the presence of a mild base to afford the correspondin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kikushima, Kotaro, Koyama, Haruka, Kodama, Kazuki, Dohi, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962002/
https://ncbi.nlm.nih.gov/pubmed/33806360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051365
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