Excess TGF-β1 Drives Cardiac Mesenchymal Stromal Cells to a Pro-Fibrotic Commitment in Arrhythmogenic Cardiomyopathy

Arrhythmogenic Cardiomyopathy (ACM) is characterized by the replacement of the myocardium with fibrotic or fibro-fatty tissue and inflammatory infiltrates in the heart. To date, while ACM adipogenesis is a well-investigated differentiation program, ACM-related fibrosis remains a scientific gap of kn...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Maione, Angela Serena, Stadiotti, Ilaria, Pilato, Chiara Assunta, Perrucci, Gianluca Lorenzo, Saverio, Valentina, Catto, Valentina, Vettor, Giulia, Casella, Michela, Guarino, Anna, Polvani, Gianluca, Pompilio, Giulio, Sommariva, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961797/
https://ncbi.nlm.nih.gov/pubmed/33800912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052673
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