ARMCX3 Mediates Susceptibility to Hepatic Tumorigenesis Promoted by Dietary Lipotoxicity

SIMPLE SUMMARY: An excess fat in the liver enhances the susceptibility to hepatic cancer. We found that Armcx3, a protein only known to date to play a role in neural development, is strongly increased in mouse liver in response to lipid availability and proliferation-inducing insults. In patients, t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Mirra, Serena, Gavaldà-Navarro, Aleix, Manso, Yasmina, Higuera, Mónica, Serrat, Román, Salcedo, María Teresa, Burgaya, Ferran, Balibrea, José Maria, Santamaría, Eva, Uriarte, Iker, Berasain, Carmen, Avila, Matias A., Mínguez, Beatriz, Soriano, Eduardo, Villarroya, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961652/
https://ncbi.nlm.nih.gov/pubmed/33807672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051110
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