The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory

Microglia, the innate immune cells of the CNS, exhibit long-term response changes indicative of innate immune memory (IIM). Our previous studies revealed IIM patterns of microglia with opposing immune phenotypes: trained immunity after a low dose and immune tolerance after a high dose challenge with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Lajqi, Trim, Marx, Christian, Hudalla, Hannes, Haas, Fabienne, Große, Silke, Wang, Zhao-Qi, Heller, Regine, Bauer, Michael, Wetzker, Reinhard, Bauer, Reinhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961448/
https://ncbi.nlm.nih.gov/pubmed/33806610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052578
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