Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) is a chronic and severe psychiatric disorder for which effective treatment options are limited. Structural and functional neuroimaging studies have consistently implicated the orbitofrontal cortex (OFC) and striatum in the pathophysiology of the disorder. Recent g...

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Udgivet i:Transl Psychiatry
Main Authors: Piantadosi, Sean C., McClain, Lora L., Klei, Lambertus, Wang, Jiebiao, Chamberlain, Brittany L., Springer, Sara A., Lewis, David A., Devlin, Bernie, Ahmari, Susanne E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961029/
https://ncbi.nlm.nih.gov/pubmed/33723209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01290-1
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