Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3β/β-Catenin Signaling

Ovarian cancer is the most lethal gynaecologic tumor, with which multi-drug resistance as the major therapeutic hindrance. Heat shock protein 90 (Hsp90) has been involved in cancer malignant behaviors. However, its role and mechanism in multi-drug resistance of ovarian cancer remains poorly understo...

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Publicado en:Front Oncol
Autores principales: Yin, Lan, Yang, Yuhan, Zhu, Wanglong, Xian, Yu, Han, Zhengyu, Huang, Houyi, Peng, Liaotian, Zhang, Kun, Zhao, Ye
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960917/
https://ncbi.nlm.nih.gov/pubmed/33738259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.620907
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