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Cyclophosphamide loaded thermo-responsive hydrogel system synergize with a hydrogel cancer vaccine to amplify cancer immunotherapy in a prime-boost manner

Although neoantigen-based cancer vaccines show great potential in cancer immunotherapy due to their ability to induce effective and long-lasting anti-tumor immunity, their development is hindered by the limitations of neoantigens identification, low immunogenicity, and weak immune response. Cyclopho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioact Mater
Hauptverfasser: Yang, Fan, Shi, Kun, Hao, Ying, Jia, Yanpeng, Liu, Qingya, Chen, Yu, Pan, Meng, Yuan, Liping, Yu, Yongyang, Qian, Zhiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: KeAi Publishing 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960683/
https://ncbi.nlm.nih.gov/pubmed/33778186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2021.03.003
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