NaCl and KCl mediate log increase in AAV vector particles and infectious titers in a specific/timely manner with the HSV platform

The increasing demand for adeno-associated virus (AAV) vectors, a result from the surging interest for their potential to cure human genetic diseases by gene transfer, tumbled on low-performing production systems. Innovative improvements to increase both yield and quality of the vector produced have...

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Vydáno v:Mol Ther Methods Clin Dev
Hlavní autoři: Yu, Chenghui, Trivedi, Prasad D., Chaudhuri, Payel, Bhake, Radhika, Johnson, Evan J., Caton, Tina, Potter, Mark, Byrne, Barry J., Clément, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960503/
https://ncbi.nlm.nih.gov/pubmed/33768125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.02.015
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