Deoxypodophyllotoxin Inhibits Non-Small Cell Lung Cancer Cell Growth by Reducing HIF-1α-Mediated Glycolysis

Cancer cell proliferation is a metabolically demanding process that requires high rate of glycolysis to support anabolic growth. Deoxypodophyllotoxin (DPT) is a natural flavonolignan with various pharmacological activities, including antitumor effect. However, whether DPT affects the metabolic repro...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Yang, Yuping, Liu, Lingling, Sun, Jinghui, Wang, Shu, Yang, Zhongyuan, Li, Honghui, Huang, Na, Zhao, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959795/
https://ncbi.nlm.nih.gov/pubmed/33732648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.629543
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