A Prospective, Phase 1 Trial of Nivolumab, Ipilimumab, and Radiotherapy in Patients with Advanced Melanoma

PURPOSE: Preclinical data suggest that radiotherapy (RT) is beneficial in combination with immune checkpoint blockade. Clinical trials have explored RT with single-agent immune checkpoint blockade, but no trials have reported RT with the combination of nivolumab and ipilimumab. PATIENTS AND METHODS:...

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Bibliografische gegevens
Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Postow, Michael A., Knox, Susan J., Goldman, Debra A., Elhanati, Yuval, Mavinkurve, Vikram, Wong, Phillip, Halpenny, Darragh, Reddy, Sunil K., Vado, Kenya, McCabe, Danielle, Aufiero Ramirez, Kristen, Macri, Mary, Schwarzenberger, Paul, Ricciardi, Toni, Ryan, Aileen, Venhaus, Ralph, Momtaz, Parisa, Shoushtari, Alexander N., Callahan, Margaret K., Chapman, Paul B., Wolchok, Jedd D., Subrahmanyam, Priyanka B., Maecker, Holden T., Panageas, Katherine S., Barker, Christopher A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959513/
https://ncbi.nlm.nih.gov/pubmed/32205463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3936
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