A Prospective, Phase 1 Trial of Nivolumab, Ipilimumab, and Radiotherapy in Patients with Advanced Melanoma

PURPOSE: Preclinical data suggest that radiotherapy (RT) is beneficial in combination with immune checkpoint blockade. Clinical trials have explored RT with single-agent immune checkpoint blockade, but no trials have reported RT with the combination of nivolumab and ipilimumab. PATIENTS AND METHODS:...

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Publicado no:Clin Cancer Res
Main Authors: Postow, Michael A., Knox, Susan J., Goldman, Debra A., Elhanati, Yuval, Mavinkurve, Vikram, Wong, Phillip, Halpenny, Darragh, Reddy, Sunil K., Vado, Kenya, McCabe, Danielle, Aufiero Ramirez, Kristen, Macri, Mary, Schwarzenberger, Paul, Ricciardi, Toni, Ryan, Aileen, Venhaus, Ralph, Momtaz, Parisa, Shoushtari, Alexander N., Callahan, Margaret K., Chapman, Paul B., Wolchok, Jedd D., Subrahmanyam, Priyanka B., Maecker, Holden T., Panageas, Katherine S., Barker, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959513/
https://ncbi.nlm.nih.gov/pubmed/32205463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3936
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