Genetic Variation in PEAR1, Cardiovascular Outcomes and Effects of Aspirin in a Healthy Elderly Population

The platelet endothelial aggregation receptor-1 (PEAR1) rs12041331 variant has been identified as a genetic determinant of platelet aggregation in response to antiplatelet therapies, including aspirin. However, association with atherothrombotic cardiovascular events is less clear, with limited evide...

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Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Lewis, Joshua P., Riaz, Moeen, Xie, Sophia, Polekhina, Galina, Wolfe, Rory, Nelson, Mark, Tonkin, Andrew M., Reid, Christopher M., Murray, Anne M., McNeil, John J., Shuldiner, Alan R., Lacaze, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959328/
https://ncbi.nlm.nih.gov/pubmed/32562573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1959
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