Disrupted inhibitory plasticity and homeostasis in Fragile X syndrome

Fragile X Syndrome (FXS) is a neurodevelopmental disorder instigated by the absence of a key translation regulating protein, Fragile X Mental Retardation Protein (FMRP). The loss of FMRP in the CNS leads to abnormal synaptic development, disruption of critical periods of plasticity, and an overall d...

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Publicado en:Neurobiol Dis
Autores principales: Cea-Del Rio, C.A., Nunez-Parra, A., Freedman, S.M., Kushner, J.K., Alexander, A.L., Restrepo, D., Huntsman, M.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959200/
https://ncbi.nlm.nih.gov/pubmed/32512151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104959
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