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Roles of CRAC channel in cancer: implications for therapeutic development

INTRODUCTION: The Ca2+release-activated Ca2+ (CRAC) channel, composed of Orai and STIM proteins, represents one of the main routes of Ca(2+) entry in most non-excitable cells. There is accumulating evidence to suggest that CRAC channel can influence various processes associated with tumorigenesis. O...

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Bibliographic Details
Published in:Expert Rev Precis Med Drug Dev
Main Authors: Khan, Husain Yar, Mazahir, Iqra, Reddy, Shriya, Fazili, Farzeen, Azmi, AsfarSohail
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959113/
https://ncbi.nlm.nih.gov/pubmed/33728379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23808993.2020.1803062
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