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P2Y(2) Receptor Antagonism Resolves Sialadenitis and Improves Salivary Flow in a Sjögren’s Syndrome Mouse Model

OBJECTIVE: Sjögren’s syndrome (SS) is a chronic autoimmune exocrinopathy characterized by lymphocytic infiltration of the salivary and lacrimal glands and decreased saliva and tear production. Previous studies indicate that the G protein-coupled P2Y(2) nucleotide receptor (P2Y(2)R) is upregulated in...

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Detalhes bibliográficos
Publicado no:Arch Oral Biol
Main Authors: Jasmer, Kimberly J., Woods, Lucas T., Forti, Kevin Muñoz, Martin, Adam L., Camden, Jean M., Colonna, Marco, Weisman, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958986/
https://ncbi.nlm.nih.gov/pubmed/33561807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.archoralbio.2021.105067
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