Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies

In cystic fibrosis (CF) airways, Pseudomonas aeruginosa forms cellular aggregates called biofilms that are thought to contribute to chronic infection. To form aggregates, P. aeruginosa can use different mechanisms, each with its own pathogenic implications. However, how they form in vivo is controve...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Jennings, Laura K., Dreifus, Julia E., Reichhardt, Courtney, Storek, Kelly M., Secor, Patrick R., Wozniak, Daniel J., Hisert, Katherine B., Parsek, Matthew R.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958924/
https://ncbi.nlm.nih.gov/pubmed/33626358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108782
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