CD28 Co-Stimulus Achieves Superior CAR T Cell Effector Function against Solid Tumors Than 4-1BB Co-Stimulus

SIMPLE SUMMARY: Efficient trafficking and survival of CAR T cells within the hostile tumor microenvironment are important prerequisites for potent solid tumor attack that have not yet been achieved. We deployed monospecific murine instead of polyclonal human T cells for CAR T cell generation to eval...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Textor, Ana, Grunewald, Laura, Anders, Kathleen, Klaus, Anika, Schwiebert, Silke, Winkler, Annika, Stecklum, Maria, Rolff, Jana, Henssen, Anton G., Höpken, Uta E., Eggert, Angelika, Schulte, Johannes H., Jensen, Michael C., Blankenstein, Thomas, Künkele, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958604/
https://ncbi.nlm.nih.gov/pubmed/33801448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051050
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados