Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development

Despite the critical role of Plasmodium sporozoites in malaria transmission, we still know little about the mechanisms underlying their development in mosquitoes. Here, we use single-cell RNA sequencing to characterize the gene expression profiles of 16,038 Plasmodium berghei sporozoites isolated th...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bogale, Haikel N., Pascini, Tales V., Kanatani, Sachie, Sá, Juliana M., Wellems, Thomas E., Sinnis, Photini, Vega-Rodríguez, Joel, Serre, David
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958459/
https://ncbi.nlm.nih.gov/pubmed/33653959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023438118
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