Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development

Despite the critical role of Plasmodium sporozoites in malaria transmission, we still know little about the mechanisms underlying their development in mosquitoes. Here, we use single-cell RNA sequencing to characterize the gene expression profiles of 16,038 Plasmodium berghei sporozoites isolated th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bogale, Haikel N., Pascini, Tales V., Kanatani, Sachie, Sá, Juliana M., Wellems, Thomas E., Sinnis, Photini, Vega-Rodríguez, Joel, Serre, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958459/
https://ncbi.nlm.nih.gov/pubmed/33653959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023438118
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