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Collagen’s enigmatic, highly conserved N-glycan has an essential proteostatic function
Intracellular procollagen folding begins at the protein’s C-terminal propeptide (C-Pro) domain, which initiates triple-helix assembly and defines the composition and chain register of fibrillar collagen trimers. The C-Pro domain is later proteolytically cleaved and excreted from the body, while the...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7958235/ https://ncbi.nlm.nih.gov/pubmed/33674390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026608118 |
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