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Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy

Prostate cancer (PC) is a potentially high-risk disease and the most common cancer in American men. It is a leading cause of cancer-related deaths in men in the US, second only to lung and bronchus cancer. Advanced and metastatic PC is initially treated with androgen deprivation therapy (ADT), but n...

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Vydáno v:Mol Pharm
Hlavní autoři: Huang, Colin T., Guo, Xin, Bařinka, Cyril, Lupold, Shawn E., Pomper, Martin G., Gabrielson, Kathleen, Raman, Venu, Artemov, Dmitri, Hapuarachchige, Sudath
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957835/
https://ncbi.nlm.nih.gov/pubmed/32803984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00457
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