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The ALS-Associated FUS (P525L) Variant Does Not Directly Interfere with Microtubule-Dependent Kinesin-1 Motility

Deficient intracellular transport is a common pathological hallmark of many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Mutations in the fused-in-sarcoma (FUS) gene are one of the most common genetic causes for familial ALS. Motor neurons carrying a mutation in the nuc...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Seifert, Anne, Drechsler, Hauke, Japtok, Julia, Korten, Till, Diez, Stefan, Hermann, Andreas
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957795/
https://ncbi.nlm.nih.gov/pubmed/33670886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052422
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