Osthol Ameliorates Kidney Damage and Metabolic Syndrome Induced by a High-Fat/High-Sugar Diet

Excessive intake of fructose results in metabolic syndrome (MS) and kidney damage, partly mediated by its metabolism by fructokinase-C or ketohexokinase-C (KHK-C). Osthol has antioxidant properties, is capable of regulating adipogenesis, and inhibits KHK-C activity. Here, we examined the potential p...

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Udgivet i:Int J Mol Sci
Main Authors: García-Arroyo, Fernando E., Gonzaga-Sánchez, Guillermo, Tapia, Edilia, Muñoz-Jiménez, Itzel, Manterola-Romero, Lino, Osorio-Alonso, Horacio, Arellano-Buendía, Abraham S., Pedraza-Chaverri, José, Roncal-Jiménez, Carlos A., Lanaspa, Miguel A., Johnson, Richard J., Sánchez-Lozada, Laura Gabriela
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957708/
https://ncbi.nlm.nih.gov/pubmed/33670975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052431
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