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Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium

Chloroquine (CQ) is an antimalarial drug known to inhibit autophagy flux by impairing autophagosome–lysosome fusion. We hypothesized that autophagy flux altered by CQ has a considerable influence on the lipid composition of endothelial cells. Thus, we investigated endothelial responses induced by CQ...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bik, Ewelina, Mateuszuk, Lukasz, Orleanska, Jagoda, Baranska, Malgorzata, Chlopicki, Stefan, Majzner, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957661/
https://ncbi.nlm.nih.gov/pubmed/33673688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052401
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