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Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium

Chloroquine (CQ) is an antimalarial drug known to inhibit autophagy flux by impairing autophagosome–lysosome fusion. We hypothesized that autophagy flux altered by CQ has a considerable influence on the lipid composition of endothelial cells. Thus, we investigated endothelial responses induced by CQ...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Bik, Ewelina, Mateuszuk, Lukasz, Orleanska, Jagoda, Baranska, Malgorzata, Chlopicki, Stefan, Majzner, Katarzyna
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957661/
https://ncbi.nlm.nih.gov/pubmed/33673688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052401
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