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Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium

Chloroquine (CQ) is an antimalarial drug known to inhibit autophagy flux by impairing autophagosome–lysosome fusion. We hypothesized that autophagy flux altered by CQ has a considerable influence on the lipid composition of endothelial cells. Thus, we investigated endothelial responses induced by CQ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Bik, Ewelina, Mateuszuk, Lukasz, Orleanska, Jagoda, Baranska, Malgorzata, Chlopicki, Stefan, Majzner, Katarzyna
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957661/
https://ncbi.nlm.nih.gov/pubmed/33673688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052401
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