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Inhibition of Inducible Nitric Oxide Synthase Prevents IL-1β-Induced Mitochondrial Dysfunction in Human Chondrocytes

Interleukin (IL)-1β is an important pro-inflammatory cytokine in the progression of osteoarthritis (OA), which impairs mitochondrial function and induces the production of nitric oxide (NO) in chondrocytes. The aim was to investigate if blockade of NO production prevents IL-1β-induced mitochondrial...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Eitner, Annett, Müller, Sylvia, König, Christian, Wilharm, Arne, Raab, Rebecca, Hofmann, Gunther O., Kamradt, Thomas, Schaible, Hans-Georg
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957659/
https://ncbi.nlm.nih.gov/pubmed/33804447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052477
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