Thromboembolic Adverse Drug Reactions in Janus Kinase (JAK) Inhibitors: Does the Inhibitor Specificity Play a Role?

Recent advances in immunology enabled the characterization of several signal transmitting pathways responsible for proper cytokine and chemokine signaling. Among them, Janus kinases (JAKs) are essential components of receptor activation systems. The discovery of JAK kinases enabled the synthesis of...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kotyla, Przemysław J., Engelmann, Małgorzata, Giemza-Stokłosa, Joanna, Wnuk, Bartosz, Islam, Md Asiful
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957632/
https://ncbi.nlm.nih.gov/pubmed/33671049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052449
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