Role of C5aR1 and C5L2 Receptors in Ischemia-Reperfusion Injury

The role of C5a receptors (C5aR1 and C5L2) in renal ischemia-reperfusion injury (IRI) is uncertain. We generated an in vitro model of hypoxia/reoxygenation with human proximal tubule epithelial cells to mimic some IRI events. C5aR1, membrane attack complex (MAC) and factor H (FH) deposits were evalu...

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Bibliografske podrobnosti
izdano v:J Clin Med
Main Authors: Arias-Cabrales, Carlos, Rodriguez-Garcia, Eva, Gimeno, Javier, Benito, David, Pérez-Sáez, María José, Redondo-Pachón, Dolores, Buxeda, Anna, Burballa, Carla, Crespo, Marta, Riera, Marta, Pascual, Julio
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957510/
https://ncbi.nlm.nih.gov/pubmed/33801177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10050974
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